Changes in Brain Wave Amplitude Due to Methadone Administration based P300 Similar Stimuli

Dwi Esti Kusumandari, Arifah Nur Istiqomah, Dessy Novita, Arjon Turnip

2019

Abstract

Drug use in Indonesia tends to be increasingly out of control where the number of users continues to increase every year. The dangers of drugs can cause various adverse effects, including psychotic behavior, convulsions, and even death due to overdose. The most dominant part disturbed by drugs is the frontal lobe of the brain, one effect is the reduced concentration of the user. To minimize this addiction, therapy with methadone (a synthetic drug to replace opioid drugs) is used. In this paper, an experiment with therapeutic patients to detect changes in brain wave amplitude due to methadone administration was carried out. EEG data recording of each subject is done using an EEG system with 19 channels. To stimulate the change in amplitude, each subject is given a stimulus that is by displaying several random images on a monitor. Each of them consists of 4 images similar to drugs referred to as non-targets and 1 image of drugs called targets. In one session all images will be displayed randomly for 10 turns (a total of 20 seconds). To minimize interference or artefacts on the recording, the data is filtered by bandpass (0.5-70 Hz) and wavelet, respectively. From this experiment it was found that significant changes in brain wave amplitude after methadone intake were obtained. These results indicate that the use of methadone is very influential on brain wave activity. The decrease is part of the reduced level of desire to consume drugs.

Paper Citation

in Harvard Style

Kusumandari D., Istiqomah A., Novita D. and Turnip A. (2019). Changes in Brain Wave Amplitude Due to Methadone Administration based P300 Similar Stimuli.In Proceedings of the International Conference on Health Informatics and Medical Application Technology - Volume 1: ICHIMAT, ISBN 978-989-758-460-2, pages 220-224. DOI: 10.5220/0009471402200224

in Bibtex Style

@conference{ichimat19,
author={Dwi Esti Kusumandari and Arifah Nur Istiqomah and Dessy Novita and Arjon Turnip},
title={Changes in Brain Wave Amplitude Due to Methadone Administration based P300 Similar Stimuli},
booktitle={Proceedings of the International Conference on Health Informatics and Medical Application Technology - Volume 1: ICHIMAT,},
year={2019},
pages={220-224},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009471402200224},
isbn={978-989-758-460-2},
}

in EndNote Style

TY - CONF

JO - Proceedings of the International Conference on Health Informatics and Medical Application Technology - Volume 1: ICHIMAT,
TI - Changes in Brain Wave Amplitude Due to Methadone Administration based P300 Similar Stimuli
SN - 978-989-758-460-2
AU - Kusumandari D.
AU - Istiqomah A.
AU - Novita D.
AU - Turnip A.
PY - 2019
SP - 220
EP - 224
DO - 10.5220/0009471402200224