Formulation of Solid Soap from the Ethanol Extract of Batak Onion as Antifungal Candida Albicans

Novita Br Ginting Munthe, Iskandar Markus Sembiring, Giana Wulandari, Rahmad Gurusinga, Sri Wulan, Ika Nur Saputri, Novidawati Boru Situmorang, Andayani Boang Manalu

2019

Abstract

Batak onion (Allium chinense) is a secondary metabolite compound that has anti-fungal activity. This study was conducted to determine the antifungal activity of ethanol extract of batak onion solid soap against Candida albicans with a concentration of 15%, 20%, 25%. Candida albicans is a normal flora that can be on the skin, genital tract, upper respiratory tract, and digestive tract including the oral cavity. An infection caused by a fungus is called candidiasis. Batak onion was extracted by diffusion method using 96% ethanol solvent. The diffusion method is used to see the antifungal activity of candida albicans. The negative control that used was Dimethyl sulfoxide (DMSO), while the positive control used was nystatin. Solid soap from batak onion extract showed antifungal activity at a concentration of 25% by inhibiting fungal growth with inhibition zone diameter of 15.35 mm and minimum inhibitory concentration at a concentration of 20% with inhibition zone diameter of 14.67 mm. The higher the concentration of ethanol extracts on the batak onion, so then the higher the diameter of the inhibitory zone in the growth of the fungus candida alibicans. This research proved that the solid soap from ethanol extract of batak onions has antifungal activity against candida albicans.

Paper Citation

in Harvard Style

Munthe N., Sembiring I., Wulandari G., Gurusinga R., Wulan S., Saputri I., Situmorang N. and Manalu A. (2019). Formulation of Solid Soap from the Ethanol Extract of Batak Onion as Antifungal Candida Albicans.In Proceedings of the International Conference on Health Informatics and Medical Application Technology - Volume 1: ICHIMAT, ISBN 978-989-758-460-2, pages 558-565. DOI: 10.5220/0009974805580565

in Bibtex Style

@conference{ichimat19,
author={Novita Br Ginting Munthe and Iskandar Markus Sembiring and Giana Wulandari and Rahmad Gurusinga and Sri Wulan and Ika Nur Saputri and Novidawati Boru Situmorang and Andayani Boang Manalu},
title={Formulation of Solid Soap from the Ethanol Extract of Batak Onion as Antifungal Candida Albicans},
booktitle={Proceedings of the International Conference on Health Informatics and Medical Application Technology - Volume 1: ICHIMAT,},
year={2019},
pages={558-565},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009974805580565},
isbn={978-989-758-460-2},
}

in EndNote Style

TY - CONF

JO - Proceedings of the International Conference on Health Informatics and Medical Application Technology - Volume 1: ICHIMAT,
TI - Formulation of Solid Soap from the Ethanol Extract of Batak Onion as Antifungal Candida Albicans
SN - 978-989-758-460-2
AU - Munthe N.
AU - Sembiring I.
AU - Wulandari G.
AU - Gurusinga R.
AU - Wulan S.
AU - Saputri I.
AU - Situmorang N.
AU - Manalu A.
PY - 2019
SP - 558
EP - 565
DO - 10.5220/0009974805580565