Discordance of Human Genotype of Papilloma Virus in Mother and Toddler with Condyloma Acuminata

Sekar Sari Arum Palupi, Prasta Bayu Putra, Kharisma Yuliasis, Dwi Retno Adi Winarni, Didik Setyo Heriyanto, Satiti Retno Pudjiati

2019

Abstract

Condylomaacuminata (CA) is a Human Papilloma Virus (HPV) infection that is rarely found in children. Transmission can be through vaginal contact, sexual abuse, auto or heteroinoculation or fomites. Polymerase Chain Reaction (PCR) examination is the gold standard for determining the cause of HPV genotype. This case report aimed to trace CA transmission to toddlers (ages <3 years). A female toddler has warts around the anus with a history of vaginal delivery and no sign of sexual abuse. The mother has warts on the genitals and between the fingers in pregnancy. The CA diagnosis was based on toddler's physical examination, acetowhite tests, and perianal biopsies. The endocervical smear from the mother was in accordance with the CA and the wart biopsy from the mother's fingers appropriate for verruca vulgaris. PCR has examined 39 HPV genotypes in the mother and the child. In the child showed HPV genotype 11, frommother’s cervical swab samplesshowed HPV genotype 87 and indeterminate result from the mother'sfingers. The discordance of HPV genotypes in the mother and the child is likely due to heteroinoculation transmission from the family who took care the child, or still possible from the mother but not detected on PCR examination because it only can examine 39 types of HPV. Identification with whole PCR is needed to ensure the source of transmission.

Paper Citation

in Harvard Style

Palupi S., Putra P., Yuliasis K., Winarni D., Heriyanto D. and Pudjiati S. (2019). Discordance of Human Genotype of Papilloma Virus in Mother and Toddler with Condyloma Acuminata.In Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI, ISBN 978-989-758-469-5, pages 338-342. DOI: 10.5220/0009988203380342

in Bibtex Style

@conference{ictromi19,
author={Sekar Sari Arum Palupi and Prasta Bayu Putra and Kharisma Yuliasis and Dwi Retno Adi Winarni and Didik Setyo Heriyanto and Satiti Retno Pudjiati},
title={Discordance of Human Genotype of Papilloma Virus in Mother and Toddler with Condyloma Acuminata},
booktitle={Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,},
year={2019},
pages={338-342},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009988203380342},
isbn={978-989-758-469-5},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,
TI - Discordance of Human Genotype of Papilloma Virus in Mother and Toddler with Condyloma Acuminata
SN - 978-989-758-469-5
AU - Palupi S.
AU - Putra P.
AU - Yuliasis K.
AU - Winarni D.
AU - Heriyanto D.
AU - Pudjiati S.
PY - 2019
SP - 338
EP - 342
DO - 10.5220/0009988203380342