Urticaria Pigmentosa in Children: A Case Report

Syafria Zidni, Elin Herlina, Retno Indar Widayati, Diah Adriani Malik, Meira Dewi Kusuma Astuti

2019

Abstract

Mastocytosis is a disorder of abnormal mast cell proliferation presented as an abnormal accumulation of mast cells in various tissues. Urticaria pigmentosa (UP) is the most common form of this disorder in children, particularly in the first year of life. Darier’s sign is pathognomonic for UP. Management for UP consists of patient education, triggering factors exposure prevention and symptomatic treatment to reduce the release of mast cells mediator.A5-year-old girl presented with brown spots and itch in various area of the body with dry skin. Physical examination found multiple hyperpigmented macules on her body, arms, legs and face. Darier’s sign was positive. Histopathology examination demonstrated mast cell granules in the superficial layer of dermis with Giemsa staining, consistent with the diagnosis of UP. There is no systemic involvement. Patient was treated with ketotifen syrup, 10% urea cream, and betamethasone valerate 0,1% cream for the erythema lesions.Ketotifen is a mast cell stabilizer that was given to relieve the symptoms of UP. Urea was given to reduce dry skin and enhance the absorption of betamethasone. Betamethasone was given to reduce the lesions of UP. After 12 weeks, patient showed some improvement in her pruritus and skin dryness. The prognosis was quo ad vitam, quo ad sanam and quo ad cosmeticam dubia ad bonam.

Paper Citation

in Harvard Style

Zidni S., Herlina E., Widayati R., Malik D. and Astuti M. (2019). Urticaria Pigmentosa in Children: A Case Report.In Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI, ISBN 978-989-758-469-5, pages 366-370. DOI: 10.5220/0009989103660370

in Bibtex Style

@conference{ictromi19,
author={Syafria Zidni and Elin Herlina and Retno Indar Widayati and Diah Adriani Malik and Meira Dewi Kusuma Astuti},
title={Urticaria Pigmentosa in Children: A Case Report},
booktitle={Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,},
year={2019},
pages={366-370},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009989103660370},
isbn={978-989-758-469-5},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,
TI - Urticaria Pigmentosa in Children: A Case Report
SN - 978-989-758-469-5
AU - Zidni S.
AU - Herlina E.
AU - Widayati R.
AU - Malik D.
AU - Astuti M.
PY - 2019
SP - 366
EP - 370
DO - 10.5220/0009989103660370