Automated 3D Labelling of Fibroblasts and Endothelial Cells in SEM-Imaged Placenta using Deep Learning

Benita S. Mackay, Sophie Blundell, Olivia Etter, Yunhui Xie, Michael D. T. McDonnel, Matthew Praeger, James Grant-Jacob, Robert Eason, Rohan Lewis, Ben Mills

2020

Abstract

Analysis of fibroblasts within placenta is necessary for research into placental growth-factors, which are linked to lifelong health and chronic disease risk. 2D analysis of fibroblasts can be challenging due to the variation and complexity of their structure. 3D imaging can provide important visualisation, but the images produced are extremely labour intensive to construct because of the extensive manual processing required. Machine learning can be used to automate the labelling process for faster 3D analysis. Here, a deep neural network is trained to label a fibroblast from serial block face scanning electron microscopy (SBFSEM) placental imaging.

Paper Citation

in Harvard Style

Mackay B., Blundell S., Etter O., Xie Y., McDonnel M., Praeger M., Grant-Jacob J., Eason R., Lewis R. and Mills B. (2020). Automated 3D Labelling of Fibroblasts and Endothelial Cells in SEM-Imaged Placenta using Deep Learning. In Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020) - Volume 2: BIOIMAGING; ISBN 978-989-758-398-8, SciTePress, pages 46-53. DOI: 10.5220/0008949700460053

in Bibtex Style

@conference{bioimaging20,
author={Benita S. Mackay and Sophie Blundell and Olivia Etter and Yunhui Xie and Michael D. T. McDonnel and Matthew Praeger and James Grant-Jacob and Robert Eason and Rohan Lewis and Ben Mills},
title={Automated 3D Labelling of Fibroblasts and Endothelial Cells in SEM-Imaged Placenta using Deep Learning},
booktitle={Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020) - Volume 2: BIOIMAGING},
year={2020},
pages={46-53},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008949700460053},
isbn={978-989-758-398-8},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020) - Volume 2: BIOIMAGING
TI - Automated 3D Labelling of Fibroblasts and Endothelial Cells in SEM-Imaged Placenta using Deep Learning
SN - 978-989-758-398-8
AU - Mackay B.
AU - Blundell S.
AU - Etter O.
AU - Xie Y.
AU - McDonnel M.
AU - Praeger M.
AU - Grant-Jacob J.
AU - Eason R.
AU - Lewis R.
AU - Mills B.
PY - 2020
SP - 46
EP - 53
DO - 10.5220/0008949700460053
PB - SciTePress