Assessment of Computational Cell Model Benefits for Optimization of Microfluidic Devices

Alžbeta Bohiniková, Inês Maia, Inês Maia, Monika Smiešková, Alžbeta Bugáňová, Ana S. Moita, Ivan Cimrák, Rui A. Lima, Rui A. Lima

2020

Abstract

This article describes the overview of the steps required to derive and validate a new model on cell behaviour in microfluidic devices, from the experimental approach to the computational model. The paper identifies the challenges of the biological side of the experiments and shows where computational power can be useful. It also emphasizes the necessity for the collaboration between the experimental and computational research groups. Computations can offer great insides into the mechanics of cells, however, interesting applications mainly arise from combining nunerics with experiments. Well calibrated and verified model can be used to improve the performance of a given microfluidic device by testing various geometries and thus lowering the number of devices that need to be produced. Choosing several designs of microfluidic devices one tries to demonstrate the wide range of possible uses of the microfluidic technology and how the computations can enrich them.

Paper Citation

in Harvard Style

Bohiniková A., Maia I., Smiešková M., Bugáňová A., Moita A., Cimrák I. and A. Lima R. (2020). Assessment of Computational Cell Model Benefits for Optimization of Microfluidic Devices. In Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020) - Volume 1: BIODEVICES; ISBN 978-989-758-398-8, SciTePress, pages 280-287. DOI: 10.5220/0009173202800287

in Bibtex Style

@conference{biodevices20,
author={Alžbeta Bohiniková and Inês Maia and Monika Smiešková and Alžbeta Bugáňová and Ana S. Moita and Ivan Cimrák and Rui A. A. Lima},
title={Assessment of Computational Cell Model Benefits for Optimization of Microfluidic Devices},
booktitle={Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020) - Volume 1: BIODEVICES},
year={2020},
pages={280-287},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009173202800287},
isbn={978-989-758-398-8},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020) - Volume 1: BIODEVICES
TI - Assessment of Computational Cell Model Benefits for Optimization of Microfluidic Devices
SN - 978-989-758-398-8
AU - Bohiniková A.
AU - Maia I.
AU - Smiešková M.
AU - Bugáňová A.
AU - Moita A.
AU - Cimrák I.
AU - A. Lima R.
PY - 2020
SP - 280
EP - 287
DO - 10.5220/0009173202800287
PB - SciTePress