Study on Interaction of Dopamine Reward Prediction Error Pathway and VTA-CA1 Novelty Pathway in VTA Region

Yaoyuan Fan

2021

Abstract

The function of dopamine neurons (DA) and the dopaminergic pathways in the brain have been studied for scientists for years. However, people still have questions about how these neural pathways interact with each other, building “bridges” between different regions of the brain. This paper investigates the mechanism of dopamine reward prediction error pathway and VTA-hippocampus novelty pathway in VTA Region, and hypothesized that there may exist some interactions between the RPE pathway and VTA- hippocampus novelty pathway in the VTA. Behavioral experiments are designed to further investigate the dopamine activity on VTA and hippocampus when the two pathways work together. The experiments will compare the DA firing in transgenic mice’s VTA and CA1 regions in the hippocampus when prediction error happens in novel environments and familiar environments. The results are predicted to show that novelty loop and RPE loop might interact with each other.

Paper Citation

in Harvard Style

Fan Y. (2021). Study on Interaction of Dopamine Reward Prediction Error Pathway and VTA-CA1 Novelty Pathway in VTA Region. In Proceedings of the 2nd Conference on Artificial Intelligence and Healthcare - Volume 1: CAIH, ISBN 978-989-758-594-4, pages 214-218. DOI: 10.5220/0011290600003444

in Bibtex Style

@conference{caih21,
author={Yaoyuan Fan},
title={Study on Interaction of Dopamine Reward Prediction Error Pathway and VTA-CA1 Novelty Pathway in VTA Region},
booktitle={Proceedings of the 2nd Conference on Artificial Intelligence and Healthcare - Volume 1: CAIH,},
year={2021},
pages={214-218},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011290600003444},
isbn={978-989-758-594-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd Conference on Artificial Intelligence and Healthcare - Volume 1: CAIH,
TI - Study on Interaction of Dopamine Reward Prediction Error Pathway and VTA-CA1 Novelty Pathway in VTA Region
SN - 978-989-758-594-4
AU - Fan Y.
PY - 2021
SP - 214
EP - 218
DO - 10.5220/0011290600003444