Metal-organic Frameworks: Preparation, Sensing, Drug Delivery, Imaging and Therapy

Wei Huang, Ruiqi Wang, Yongli Zhang

2021

Abstract

Metal-organic frameworks (MOFs) materials have been widely used in biomedical field due to their unique physical-chemical properties. This review summarized the preparation methods for MOFs, including hydrothermal or solvothermal method, microwave synthesis, ultrasonic synthesis, mechanical method and aerosol method. The MOFs synthesized by hydrothermal method exhibit uniform morphology. Moreover, the properties of MOFs can be controlled by changing the concentration of precursors, the types of solvents and catalysts. For the mechanical method, MOFs can be obtained by the mixing and grinding of raw materials in a small amount of solvent without external heating. This method is applied for the large-scale production of MOFs due to the simple operation, high yield and low energy consumption. With the advantages of large specific surface area, high porosity, easy modification, low toxicity and biodegradability, this review also focused in various biomedical applications of MOFs, such as fluorescence sensing, drug delivery, bioimaging and tumor therapy.

Paper Citation

in Harvard Style

Huang W., Wang R. and Zhang Y. (2021). Metal-organic Frameworks: Preparation, Sensing, Drug Delivery, Imaging and Therapy. In Proceedings of the 2nd Conference on Artificial Intelligence and Healthcare - Volume 1: CAIH, ISBN 978-989-758-594-4, pages 230-237. DOI: 10.5220/0011291000003444

in Bibtex Style

@conference{caih21,
author={Wei Huang and Ruiqi Wang and Yongli Zhang},
title={Metal-organic Frameworks: Preparation, Sensing, Drug Delivery, Imaging and Therapy},
booktitle={Proceedings of the 2nd Conference on Artificial Intelligence and Healthcare - Volume 1: CAIH,},
year={2021},
pages={230-237},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011291000003444},
isbn={978-989-758-594-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd Conference on Artificial Intelligence and Healthcare - Volume 1: CAIH,
TI - Metal-organic Frameworks: Preparation, Sensing, Drug Delivery, Imaging and Therapy
SN - 978-989-758-594-4
AU - Huang W.
AU - Wang R.
AU - Zhang Y.
PY - 2021
SP - 230
EP - 237
DO - 10.5220/0011291000003444