Voronoi Diagrams and Perlin Noise for Simulation of Irregular Artefacts in Microscope Scans

Atef Alreni, Galina Momcheva, Galina Momcheva, Stoyan Pavlov, Stoyan Pavlov

2022

Abstract

Artefacts are a common occurrence in microscopic images and scans used in life science research. The artefacts may be regular and irregular and arise from different sources: distortions of the illumination field, optical aberrations, foreign particles in the illumination and optical path, errors, irregularities during the processing and staining phases, et cetera. While several computational approaches for dealing with patterned distortions exist, there is no universal, efficient, reliable, and facile method for removing irregular artefacts. This leaves life scientists within cumbersome predicaments, wastes valuable time, and may alter the analysis results. In this article, the authors outline a systematic way to introduce synthetic irregular artefacts in microscopic scans via Perlin Noise and Voronoi Diagrams. The reasoning behind such a task is to produce pairs of “successful” and manufactured “failed” image counterparts to be used as training pairs in an artificial neural network tuned for artefact removal. At the moment, the outlined method only works for grayscale images.

Paper Citation

in Harvard Style

Alreni A., Momcheva G. and Pavlov S. (2022). Voronoi Diagrams and Perlin Noise for Simulation of Irregular Artefacts in Microscope Scans. In Proceedings of the 15th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2022) - Volume 2: BIOIMAGING; ISBN 978-989-758-552-4, SciTePress, pages 117-122. DOI: 10.5220/0010833000003123

in Bibtex Style

@conference{bioimaging22,
author={Atef Alreni and Galina Momcheva and Stoyan Pavlov},
title={Voronoi Diagrams and Perlin Noise for Simulation of Irregular Artefacts in Microscope Scans},
booktitle={Proceedings of the 15th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2022) - Volume 2: BIOIMAGING},
year={2022},
pages={117-122},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010833000003123},
isbn={978-989-758-552-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 15th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2022) - Volume 2: BIOIMAGING
TI - Voronoi Diagrams and Perlin Noise for Simulation of Irregular Artefacts in Microscope Scans
SN - 978-989-758-552-4
AU - Alreni A.
AU - Momcheva G.
AU - Pavlov S.
PY - 2022
SP - 117
EP - 122
DO - 10.5220/0010833000003123
PB - SciTePress