The Metabolic Mechanism of Satiety Signal and Adiposity Signal on Food Intake Regulation

Bochen Li

2022

Abstract

Obesity rates rose sharply in past 40 years, owing to the availability of appetizing food and work-related sedentary habits. Obesity is caused by a long-term positive energy balance, but by reducing food intake significant weight loss can be achieved. Food intake is simultaneously regulated by biochemical signals (homeostasis) and social factors (non-homeostasis). As two important homeostasis factors, satiety and adiposity signals have been well studied, but it is relatively fragmented. Therefore, this study looks at satiety and adiposity signals to understand the metabolic mechanism of human food related metabolic pathways from the perspective of homeostasis factor. Satiety and adiposity signals are critical for reducing obesity, because they play such a large role in appetite control to reduce food intake. This research analyses literature about satiety and adiposity signals, such as references related to CCK, GLP-1, ghrelin, leptin and insulin, and combines the research of exogenous injection satiety and adiposity signals for calorie restriction to better illustrate the metabolic pathways of these hormones.Through the analysis of these factors, it is concluded that satiety and adiposity signals are expressed on two neuron pathways via NTS and ARC to synergeticly control food intake by regulating appetite, but it seems that the method of injecting exogenous hormones to treat obesity is currently difficult to achieve.

Paper Citation

in Harvard Style

Li B. (2022). The Metabolic Mechanism of Satiety Signal and Adiposity Signal on Food Intake Regulation. In Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH, ISBN 978-989-758-596-8, pages 144-150. DOI: 10.5220/0011234400003438

in Bibtex Style

@conference{ichih22,
author={Bochen Li},
title={The Metabolic Mechanism of Satiety Signal and Adiposity Signal on Food Intake Regulation},
booktitle={Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH,},
year={2022},
pages={144-150},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011234400003438},
isbn={978-989-758-596-8},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH,
TI - The Metabolic Mechanism of Satiety Signal and Adiposity Signal on Food Intake Regulation
SN - 978-989-758-596-8
AU - Li B.
PY - 2022
SP - 144
EP - 150
DO - 10.5220/0011234400003438