Lipoproteins and Atherosclerotic Cardiovascular Diseases

Jingying Wang

2022

Abstract

Metabolisms of triglycerides and cholesterol from both the intestine and the liver are important in humans. Generally, there are three lipoprotein pathways involving chylomicrons, chylomicron remnants, VLDL, LDL, and HDL. Started in arterial endothelium, accumulation of LDL and proteoglycans will form oxidized LDL and lead to arterial macrophages. Then, macrophage foam cells will enhance plaque progression. If the plaque is unstable, it is very likely to develop plaque rupture and form thrombus. To better understand the mechanism and find medications, it is important to choose adequate animal models based on lipid metabolism and characteristics of atherosclerosis. The combination of statistical models in recent studies helps to examine the effects of two independent factors on one dependent factor.

Paper Citation

in Harvard Style

Wang J. (2022). Lipoproteins and Atherosclerotic Cardiovascular Diseases. In Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH, ISBN 978-989-758-596-8, pages 404-409. DOI: 10.5220/0011371300003438

in Bibtex Style

@conference{ichih22,
author={Jingying Wang},
title={Lipoproteins and Atherosclerotic Cardiovascular Diseases},
booktitle={Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH,},
year={2022},
pages={404-409},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011371300003438},
isbn={978-989-758-596-8},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH,
TI - Lipoproteins and Atherosclerotic Cardiovascular Diseases
SN - 978-989-758-596-8
AU - Wang J.
PY - 2022
SP - 404
EP - 409
DO - 10.5220/0011371300003438