Altered Small-World Topological Properties of Functional Brain Network in Patients with OSA

Ailin Hou, Ailin Hou, Xueming Pang, Quan Zhang

2022

Abstract

Obstructive sleep apnea (OSA) is a common disorder of sleep disorders in which patients often suffer from cognitive impairment. Recent neurological imaging studies have shown that cognitive impairment in OSA patients is closely related to the extensive brain regions with abnormal neural activity. However, it remains unclear whether the topological properties of function networks in OSA patients have changed. Based on resting-states functional magenetic resonance imaging (rs-fMRI) and graph-analysis methods, this study explores the different orgnization in functional brain network between OSA patients and healthy volunteers. The brain connectome of patients with OSA exhibited small-worldness, but existed significant statistical difference compared with health controls. Besides, the betweenness centrality and degree centrality of right dorsolateral superior frontal gyrus and right hippocampal gyrus were significantly different in OSA patient group. The aberrant topological properties illustrated that the functional integration and segregation of brain networks in patients with OSA were disrupted.

Paper Citation

in Harvard Style

Hou A., Pang X. and Zhang Q. (2022). Altered Small-World Topological Properties of Functional Brain Network in Patients with OSA. In Proceedings of the 4th International Conference on Biotechnology and Biomedicine - Volume 1: ICBB; ISBN 978-989-758-637-8, SciTePress, pages 27-30. DOI: 10.5220/0012012400003633

in Bibtex Style

@conference{icbb22,
author={Ailin Hou and Xueming Pang and Quan Zhang},
title={Altered Small-World Topological Properties of Functional Brain Network in Patients with OSA},
booktitle={Proceedings of the 4th International Conference on Biotechnology and Biomedicine - Volume 1: ICBB},
year={2022},
pages={27-30},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0012012400003633},
isbn={978-989-758-637-8},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 4th International Conference on Biotechnology and Biomedicine - Volume 1: ICBB
TI - Altered Small-World Topological Properties of Functional Brain Network in Patients with OSA
SN - 978-989-758-637-8
AU - Hou A.
AU - Pang X.
AU - Zhang Q.
PY - 2022
SP - 27
EP - 30
DO - 10.5220/0012012400003633
PB - SciTePress