Description of PD Phonation in Terms of EEG-Related Frequency Bands

Pedro Gómez, Jiří Mekyska, Luboš Brabenec, Patrik Šimko, Irena Rektorová, Andrés Gómez, Victoria Rodellar

2023

Abstract

Parkinson’s Disease (PD) is an increasing prevalence neurodegenerative condition affecting the life quality of people suffering from its neuromotor and cognitive performance. PD symptoms include vocalization and speech alterations, known as hypokinetic dysarthria (HD). One of the manifestations of HD is unstable phonation. Repetitive Transcranial Magnetic Stimulation (rTMS) is a non-invasive method that may improve some motor and non-motor symptoms of persons with PD (PwP). The present study concentrates on analyzing and comparing the phonation behavior of two cases before (pre-stimulus) and after (post-stimulus) ten sessions of rTMS treatment, to assess the extent of changes in their vocalization. Voice recordings of a sustained vowel [a:] taken immediately before and after the treatment, and at follow-up sessions (at six, ten, and fourteen weeks after the baseline assessment) were processed by inverse filtering to estimate a biomechanical correlate of vocal fold stiffness, which band-pass filtered into EEG-related frequency bands. Log-likelihood ratios between pre- and post-stimulus amplitude distributions of each frequency band, Mann-Whitney U-tests, and normalized difference scores showed significant improvements in the actively stimulated case, which were not observed in the sham case. Early preliminary insights into the capability of phonation quality assessment on monitoring neuromechanical activity from acoustic signals are shown.

Paper Citation

in Harvard Style

Gómez P., Mekyska J., Brabenec L., Šimko P., Rektorová I., Gómez A. and Rodellar V. (2023). Description of PD Phonation in Terms of EEG-Related Frequency Bands. In Proceedings of the 16th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2023) - Volume 4: BIOSIGNALS; ISBN 978-989-758-631-6, SciTePress, pages 226-233. DOI: 10.5220/0011669100003414

in Bibtex Style

@conference{biosignals23,
author={Pedro Gómez and Jiří Mekyska and Luboš Brabenec and Patrik Šimko and Irena Rektorová and Andrés Gómez and Victoria Rodellar},
title={Description of PD Phonation in Terms of EEG-Related Frequency Bands},
booktitle={Proceedings of the 16th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2023) - Volume 4: BIOSIGNALS},
year={2023},
pages={226-233},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011669100003414},
isbn={978-989-758-631-6},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 16th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2023) - Volume 4: BIOSIGNALS
TI - Description of PD Phonation in Terms of EEG-Related Frequency Bands
SN - 978-989-758-631-6
AU - Gómez P.
AU - Mekyska J.
AU - Brabenec L.
AU - Šimko P.
AU - Rektorová I.
AU - Gómez A.
AU - Rodellar V.
PY - 2023
SP - 226
EP - 233
DO - 10.5220/0011669100003414
PB - SciTePress