Vitamin D Levels Among Breast Cancer Patients in a Tertiary Hospital in Lampung, Indonesia

Indri Windarti, Bintang Abadi Siregar, Rizki Hanriko, Aditya Kusumaningtyas, Bayu Putra Danan Jaya

2023

Abstract

Introduction: Vitamin D levels can vary among populations due to geographical location and sun exposure, dietary habits, lifestyle, and genetic factors. People living in Indonesia may have a higher potential for sun exposure, which can lead to adequate vitamin D synthesis in the skin. Several studies have suggested a potential protective role of vitamin D against breast cancer. Preclinical studies have shown that vitamin D may inhibit the growth and spread of breast cancer cells, induce cell death, and inhibit angiogenesis. Some studies have found an inverse association, suggesting that higher vitamin D levels may be associated with a reduced risk of breast cancer. This study was conducted to obtain the most recent information about the vitamin D levels of breast cancer patients of Indonesian women, especially in Lampung. Methods: We performed an observational analysis in an ongoing prospective cohort study of breast cancer patients at Dr. H. Abdul Moeloek Hospital, Bandar Lampung, Indonesia. Sixty-eight subjects were collected from the main study. Information on subjects, sociodemographic characteristics, clinical status, and tumor profile was assessed. Vitamin D level was measured using ELISA methods. The association between sociodemographic and clinical profiles with vitamin D levels was tested using Chi-square. Results: Breast cancer patients' mean vitamin D level was low (19.7  6.4 ng/ml). There was no correlation between sun exposure, sociodemographic, and clinical status to Vitamin D levels of breast cancer patients. Patients with comorbidity tend to have a low vitamin D level, primarily type 2 diabetes. Conclusion: Low vitamin D levels are frequently found in our population. Further information about vitamin D levels and their association with the survival of breast cancer patients is still challenging to become research questions.

Paper Citation

in Harvard Style

Windarti I., Siregar B., Hanriko R., Kusumaningtyas A. and Jaya B. (2023). Vitamin D Levels Among Breast Cancer Patients in a Tertiary Hospital in Lampung, Indonesia. In Proceedings of the 5th International Conference on Social Determinants of Health - Volume 1: ICSDH; ISBN 978-989-758-727-6, SciTePress, pages 130-137. DOI: 10.5220/0012901800004564

in Bibtex Style

@conference{icsdh23,
author={Indri Windarti and Bintang Siregar and Rizki Hanriko and Aditya Kusumaningtyas and Bayu Jaya},
title={Vitamin D Levels Among Breast Cancer Patients in a Tertiary Hospital in Lampung, Indonesia},
booktitle={Proceedings of the 5th International Conference on Social Determinants of Health - Volume 1: ICSDH},
year={2023},
pages={130-137},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0012901800004564},
isbn={978-989-758-727-6},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 5th International Conference on Social Determinants of Health - Volume 1: ICSDH
TI - Vitamin D Levels Among Breast Cancer Patients in a Tertiary Hospital in Lampung, Indonesia
SN - 978-989-758-727-6
AU - Windarti I.
AU - Siregar B.
AU - Hanriko R.
AU - Kusumaningtyas A.
AU - Jaya B.
PY - 2023
SP - 130
EP - 137
DO - 10.5220/0012901800004564
PB - SciTePress