A Novel Cuff-Less and Calibration-Free Blood Pressure Estimation Framework Using Single Photoplethysmogram

Yusuf Hayirlioglu, Beren Semiz

2025

Abstract

Blood pressure (BP) is one of the four main vital signs and is a key indicator of cardiovascular health. However, monitoring of BP is not regularly done in most of the population until health problems arise. Continuous and convenient monitoring of blood pressure is thus needed to address this issue. We propose a novel BP estimation algorithm without calibration to estimate BP from a cuff-less photoplethysmogram (PPG) system. Data from a total of 219 subjects, which underwent only simple preprocessing steps, was used to train and evaluate a hybrid Convolutional Long Short-Term Memory Neural Network (CNN-LSTM) model. The model was trained using the preprocessed PPG signal as the only input. The model had two neurons in the last layer to output systolic blood pressure (SBP) and diastolic blood pressure (DBP) values. The model was optimized by conducting a random search on its hyperparameters for better performance. The model resulted in a comparable performance to those in the literature, with mean absolute errors (MAEs) of 14.13 mmHg and 8.80 mmHg for SBP and DBP, respectively. To assess generalizability, we also tested the trained model on a second dataset collected from 20 subjects using a custom wearable system, which was again resulted in MAEs of 10.71 mmHg and 10.09 mmHg, respectively. Overall, our results show that such a pipeline could potentially be leveraged in the design of wearable systems to achieve cuff-less and calibration-free BP monitoring in ambulatory settings.

Paper Citation

in Harvard Style

Hayirlioglu Y. and Semiz B. (2025). A Novel Cuff-Less and Calibration-Free Blood Pressure Estimation Framework Using Single Photoplethysmogram. In Proceedings of the 18th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIOSIGNALS; ISBN 978-989-758-731-3, SciTePress, pages 697-703. DOI: 10.5220/0013055600003911

in Bibtex Style

@conference{biosignals25,
author={Yusuf Hayirlioglu and Beren Semiz},
title={A Novel Cuff-Less and Calibration-Free Blood Pressure Estimation Framework Using Single Photoplethysmogram},
booktitle={Proceedings of the 18th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIOSIGNALS},
year={2025},
pages={697-703},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0013055600003911},
isbn={978-989-758-731-3},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 18th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIOSIGNALS
TI - A Novel Cuff-Less and Calibration-Free Blood Pressure Estimation Framework Using Single Photoplethysmogram
SN - 978-989-758-731-3
AU - Hayirlioglu Y.
AU - Semiz B.
PY - 2025
SP - 697
EP - 703
DO - 10.5220/0013055600003911
PB - SciTePress