Enhanced YOLOv8 Framework for Early Detection of Alzheimer's Disease Using MRI Scans

Safa Jraba, Mohamed Elleuch, Hela Ltifi, Monji Kherallah

2025

Abstract

Alzheimer's disease is characterized by a progressive neurodegenerative disorder, often misdiagnosed too late, with early symptoms that are hidden. Detection is crucial for effective treatment and slowing the progression of disease. We propose an upgraded version of the YOLO (You Only Look Once) framework, namely YOLOv8, for detecting Alzheimer's disease from MRI scans. Our approach seeks the detection of early structural changes in the brain, most particularly in the hippocampus and cortex, which are also among the first areas affected in this disease process. The framework performs state-of-the-art detection of Alzheimer's changes with a 96% precision via multi-scale feature extraction specifically designed for neuroimaging data. Results show this approach to be exceptionally effective in improving sensitivity and precision over existing techniques, marking it as a highly reliable method for early diagnosis of Alzheimer's disease.

Paper Citation

in Harvard Style

Jraba S., Elleuch M., Ltifi H. and Kherallah M. (2025). Enhanced YOLOv8 Framework for Early Detection of Alzheimer's Disease Using MRI Scans. In Proceedings of the 17th International Conference on Agents and Artificial Intelligence - Volume 3: ICAART; ISBN 978-989-758-737-5, SciTePress, pages 1229-1237. DOI: 10.5220/0013315300003890

in Bibtex Style

@conference{icaart25,
author={Safa Jraba and Mohamed Elleuch and Hela Ltifi and Monji Kherallah},
title={Enhanced YOLOv8 Framework for Early Detection of Alzheimer's Disease Using MRI Scans},
booktitle={Proceedings of the 17th International Conference on Agents and Artificial Intelligence - Volume 3: ICAART},
year={2025},
pages={1229-1237},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0013315300003890},
isbn={978-989-758-737-5},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 17th International Conference on Agents and Artificial Intelligence - Volume 3: ICAART
TI - Enhanced YOLOv8 Framework for Early Detection of Alzheimer's Disease Using MRI Scans
SN - 978-989-758-737-5
AU - Jraba S.
AU - Elleuch M.
AU - Ltifi H.
AU - Kherallah M.
PY - 2025
SP - 1229
EP - 1237
DO - 10.5220/0013315300003890
PB - SciTePress